H-Cube Mini Plus Flow Reactor System

Procurement Summary

The Department of Health and Human Services (HHS), National Institutes of Health (NIH), National Institute of Child Health and Human Development (NICHD), on behalf of National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), is requesting approval for an exception to the Buy American Statute (BA). The NIDDK is involved in the discovery and development of new molecules with medicinal value or for applications to diagnostics. Some of these molecules have the potential to become therapeutics or to be used as important components in diagnostic applications that signal the presence of disease. Applications in either area are of great benefit to human health and thus to NIDDK's mission. Research conducted in the NIDDK Synthetic Bioactive Molecules Section (SBMS), Laboratory of Bioorganic Chemistry (LBC) involves synthesis and purification of biologically active molecules called thyclotides, which helps support their research goal to develop the next generation of diagnostics and therapeutics to detect and treat human diseases. This requirement is for H-cube mini system equipment, which is needed by the lab to make thyclotides, specifically the monomeric units used to build thyclotides.

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