Sartorius Streptavidin (SA) Biosensors

Procurement Summary

The Vaccine Research Center (VRC) Virology Laboratory comprises the Virology, Humoral Immunology, and Structural Biology Sections and related Cores. The goal of the Virology Laboratory is to conduct research to understand better the cellular and molecular regulation of viral gene expression, viral entry into the host cell, optimization of immune responses to gene-based vaccination which correlates to immune protection, assessment of active and passive approaches for HIV-1 vaccine development, and to apply structural biology techniques toward rational vaccine design for emerging and re-emerging infectious diseases. The VRC is developing vaccines for HIV-1 and other viruses. Currently, SBS/SBIS is working on developing vaccines for SARS-CoV-2. The production of wild-type and mutant viral proteins, and anti-viral antibodies is critical in vaccine development. Making specific immunogens as probes is critical in order to isolate antibodies and develop therapeutic agents in the COVID-19 treatment. This request is for purchasing Streptavidin (SA) Biosensors from Sartorius Corporation for measuring protein-protein interactions, including Sera readout in ongoing immunization experiments on an Octet instrument. Material no. 18-5064 $12,110 (20 Trays) @ 1 = $13,650.00 Streptavidin (SA) Biosensors- Twenty trays of 96 biosensors coated with streptavidin for quantitation, screening, or kinetic applications. Material no. 18-5064 $12,110 (20 Trays) @ 1= $12,110.00 Streptavidin (SA) Biosensors- Twenty trays of 96 biosensors coated with streptavidin for quantitation, screening, or kinetic applications. Material no. 18-5103 $14,020 (20 Trays) @ 1 = $14,020.00 NI-NTA (NTA) Biosensors- Twenty trays of 96 biosensors coated with nickel-charged tris-NTA for both quantitation and kintetic applications of HIS-tagged molecules. Material no. 18-5122 $13,960 (20 Trays) @ 1 = $13,960.00 NI-NTA (NTA) Biosensors- Twenty trays of 96 biosensors coated with nickel-charged tris-NTA for both quantitation and kinetic applications of HIS-tagged molecules. These requested items are consumables for the Octet machine purchased from Sartious for kinetic analysis. Manufacturer: Sartorius Corporation

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