Sartorius Streptavidin (SA) Biosensors
Waiver type - Procurement: Nonavailability
Agency: NATIONAL INSTITUTES OF HEALTH (7529) • Product Service Code (PSC) : 6505 | Last Modified: 05/22/2024
Procurement Summary
The Vaccine Research Center (VRC) Virology Laboratory comprises the Virology, Humoral Immunology, and Structural Biology Sections and related Cores. The goal of the Virology Laboratory is to conduct research to understand better the cellular and molecular regulation of viral gene expression, viral entry into the host cell, optimization of immune responses to gene-based vaccination which correlates to immune protection, assessment of active and passive approaches for HIV-1 vaccine development, and to apply structural biology techniques toward rational vaccine design for emerging and re-emerging infectious diseases. The VRC is developing vaccines for HIV-1 and other viruses. Currently, SBS/SBIS is working on developing vaccines for SARS-CoV-2. The production of wild-type and mutant viral proteins, and anti-viral antibodies is critical in vaccine development. Making specific immunogens as probes is critical in order to isolate antibodies and develop therapeutic agents in the COVID-19 treatment. This request is for purchasing Streptavidin (SA) Biosensors from Sartorius Corporation for measuring protein-protein interactions, including Sera readout in ongoing immunization experiments on an Octet instrument. Material no. 18-5064 $12,110 (20 Trays) @ 1 = $13,650.00 Streptavidin (SA) Biosensors- Twenty trays of 96 biosensors coated with streptavidin for quantitation, screening, or kinetic applications. Material no. 18-5064 $12,110 (20 Trays) @ 1= $12,110.00 Streptavidin (SA) Biosensors- Twenty trays of 96 biosensors coated with streptavidin for quantitation, screening, or kinetic applications. Material no. 18-5103 $14,020 (20 Trays) @ 1 = $14,020.00 NI-NTA (NTA) Biosensors- Twenty trays of 96 biosensors coated with nickel-charged tris-NTA for both quantitation and kintetic applications of HIS-tagged molecules. Material no. 18-5122 $13,960 (20 Trays) @ 1 = $13,960.00 NI-NTA (NTA) Biosensors- Twenty trays of 96 biosensors coated with nickel-charged tris-NTA for both quantitation and kinetic applications of HIS-tagged molecules. These requested items are consumables for the Octet machine purchased from Sartious for kinetic analysis. Manufacturer: Sartorius Corporation
Waiver Rationale Summary
Based on the above market research findings and results from solicitations for these biosensors that were posted on SAM.gov, no domestic products that meet the requirements were identified. No domestically manufactured biosensors meet the government needs and threatens the research and integrity of the data that is shared across labs. Historically, only one quote for foreign supplies had been received when reviewing previous solicitations. The feasibility of foregoing the requirement is not an option as it would be a costly set back to the government. Based on findings detailed above, it has hereby determined by NIAID, consistent with FAR 25.103(b)(2), that these items are not domestically available.
Yes
Yes
Consistent with Policy
DRUGS AND BIOLOGICALS
325414 - Biological Product (except Diagnostic) Manufacturing
05/06/2024
N/A
Pre-solicitation
0 - 6 months
Individual Waiver
NATIONAL INSTITUTES OF HEALTH