Coil Cooler for Cool Coils and High Performance Option/Refrigeration Unit for Coil Cooler

Procurement Summary

A coil cooling unit is needed to support the Study entitled, “Role of GABAergic transmission in auditory processing in Autism Spectrum Disorder”. This coil cooling unit is an essential component for a complete TMS system. A coil cooling unit is fundamental for use of the liquid cooled coil, which is also being requested in order to carry out our study, which has been reviewed and approved by the NIMH committee for the Scientific Review of Protocols (CSRP) and by the NIH IRB. As part of the study, TMS pulses must be applied repeatedly, which may result in coil overheating. The coil cooling unit keeps the coils from overheating and maintains the temperature of the coils between 18 and 20°C at all time. The existing system does not have a coil cooling unit as it has not previously been used for repetitive stimulation protocols. The coil cooling unit requested here will allow for the study to utilize existing equipment currently in the Noninvasive Neuromodulation Unit. The blinded, cooled coil will allow for the targeted stimulation of language processing networks within the brain in order to transiently modulate the putative brain mechanism, GABAergic transmission. In doing so, we aim to define the causal link between the putative mechanism and the neurological and behavioral phenotype of ASD. The liquid coil cooling system and a refrigeration cooling unit keeps the coils from overheating and maintains the temperature of the coils between 18 and 20°C at all time.

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