Miltenyi Biotec’s autoMACS NEO Separator
Waiver type - Procurement: Nonavailability
Agency: NATIONAL INSTITUTES OF HEALTH (7529) • Product Service Code (PSC) : 6640 | Last Modified: 08/23/2023
Procurement Summary
1x Quantity of Miltenyi Biotec’s autoMACS NEO Separator with the MiniSampler component. This item is manufactured by Miltenyi Biotec in Germany and will be used to support the mission of the National Institute of Allergy & Infectious Diseases (NIAID). The National Institute of Allergy & Infectious Diseases (NIAID)’s Laboratory of Immunogenetics Autoimmunity (LIA), Functional Genomics Section (AFGS) (collectively “Program”) is working to identify genetic and environmental modifiers of Autoimmune Diseases. To this end, Program needs to study the function of specific immune cells population during inflammation, autoimmune disease or after cellular activation with various stimuli. A Cell Separator Instrument with a MACS MiniSampler S is required to get various purified immune cells population simultaneously from tissues. The autoMACS® NEO Separator Instrument with a MACS MiniSampler S (Manufacturer, Miltenyi Biotec) is a compact, high performance immunomagnetic cell separation instrument with fully automated functions for hands- free operation, such as fully automated labeling of multiple samples. To complement this equipment, Myltenyi Biotec provides optimized protocols that are specifically designed to purify immune cells from various tissues of the mouse. The MACS MiniSampler S is an accessory for the autoMACS NEO Separator and is intended to be used only in combination with this instrument for automated magnetic cell separation. Purification and characterization of different immune cell populations from mouse tissue is an essential experimental step in Program’s research protocols. The autoMACS® NEO machine, together with associated accessory, reagents and optimized protocols, cover all of Program’s needs with the required specifications. This machine will be used for immune cell separation by many Investigators in Program’s Lab at 5625FL/4N03A for the research project entitled: AI000912 Genetic and Environmental Modifiers of Autoimmune Disease. This acquisition has unique technical and compatibility requirements. Not only does this equipment meet Program’s required technical requirements, but it also meets Program’s compatibility requirements. The need for this specific machine is to continue research that was initiated with an autoMACS Pro cell separator from Miltenyi Biotech that will be replaced with this new autoMACS® NEO Separator Instrument plus a MACS MiniSampler S from the same manufacturer, Miltenyi Biotec. Program needs to continue identical experimental protocols and use the same reagents so Program can have consistent data to combine with data already collected. AutoMACS equipment was originally selected because it is consistently precise, reliable and efficient in cell purification protocols. Program have validated and verified all of our protocols using the autoMACS system, thus continuing with the same machine would be the most efficient use of laboratory resources. The only source and instrument known to meet these requirements is this autoMACS NeoSeparator, which is manufactured by Miltenyi Biotec in Germany.
Waiver Rationale Summary
Based on the above market research findings and results from the brand name or equal request for quotes RFQ-NIAID-23-2180395 posted on SAM.gov, no domestic products that meet the requirements were available. No domestically manufactured items that meet the Government’s need that are mined, produced, or manufactured in the United States in sufficient and reasonably available commercial quantities and of satisfactory quality could be identified. Only one company responded to the solicitation (Request for Quotes), which was posted as full and open competition with a brand name or equal requirement, and that was Miltenyi Biotech. The feasibility of foregoing the requirement or providing a United States manufactured substitute has been considered, and no substitutes were found. Authority is requested to acquire the above-described autoMACs NeoSeparator, manufactured by Miltenyi in Germany. Based on the findings detailed above, the autoMACs NeoSeparator, manufactured by Miltenyi are not mined, produced, or manufactured in the United States in sufficient and reasonably available commercial quantities and of a satisfactory quality. Therefore, it is hereby determined by NIAID, consistent with FAR 25.103(b)(2), that these items are not domestically available.
Yes
Yes
Consistent with Policy
LABORATORY EQUIPMENT AND SUPPLIES
334516 - Analytical Laboratory Instrument Manufacturing
08/21/2023
RFQ-NIAID-23-2180395 SS-NIAID-23-2180395
RFQ-NIAID-23-2180395
Post-solicitation
0 - 6 months
Individual Waiver
NATIONAL INSTITUTES OF HEALTH