DNA Extractor
Waiver type - Procurement: Nonavailability
Agency: NATIONAL INSTITUTES OF HEALTH (7529) • Product Service Code (PSC) : 6640 | Last Modified: 02/13/2025
Procurement Summary
The required DNA Extractor contains the following salient characteristics: • Automated purification of nucleic acids from blood, serum, plasma, viral transport media, cells, swabs, and saliva suitable for use in PCR and NGS applications. • Purification method that uses sample lysis and binding to paramagnetic particles as the primary separation principle. • Utilization of a low elution volume (LEV) format for sample processing allowing for maximum nucleic acid concentration. • Automated processing of 1 to 16 samples per purification run with run times between 23-70 minutes. • Heated elution to improve yields. • Pre-filled reagent cartridges. • Pre-loaded extraction protocols for each type of starting material. • Quantus"' Fluorimeter for quantification of nucleic acids and proteins. • Integration with Liquid Handler for automated pre- and post-extraction sample preparation. • Portal software for seamless passing of sample tracking data from one instrument module to the next.
Waiver Rationale Summary
All of the salient characteristics above are required. The NIA lab cannot successfully perform nucleic acid sequencing analysis to support neurodegenerative disease research if the extractor does not include these characteristics. The NIA lab is pioneering large-scale long-read genetic sequencing efforts for Alzheimer's disease and Alzheimer’s disease related dementias. NIA’s publicly available long-read datasets are designed to accelerate understanding of the genetic architecture of Alzheimer's disease and Alzheimer’s disease related dementias.
Yes
Yes
Consistent with Policy
LABORATORY EQUIPMENT AND SUPPLIES
334516 - Analytical Laboratory Instrument Manufacturing
01/21/2025
N/A
Pre-solicitation
Instant Delivery Only
Individual Waiver
NATIONAL INSTITUTES OF HEALTH