LIFE TECHNOLOGIES CYTOKINE 30-PLEX HUMAN PANEL (AMBIS 2230371)
Waiver type - Procurement: Nonavailability
Agency: NATIONAL INSTITUTES OF HEALTH (7529) • Product Service Code (PSC) : 6505 | Last Modified: 08/12/2024
Procurement Summary
The National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), conducts and supports basic and applied research to better understand, treat, and ultimately prevent infectious, immunologic, and allergic diseases. Within NIAID, the Laboratory of Infectious Disease (LID) has a long history of vaccine development and identification of new agents of viral diseases. Within the LID, the Viral Epidemiology and Immunity Unit (VEIU) uses a multidisciplinary approach to investigate immunological protection against and susceptibility to emerging and re-emerging viral diseases with the goal of informing how vaccines can be effectively and safely licensed and introduced through vaccination programs. The VEIU has a current requirement for Cytokine 30-plex Human Panel multiplex ELISA-based assay (Luminex) to measure the cytokines and chemokines in order to 1) comprehensively describe the immune biomarkers and kinetics in response to vaccination 2) elucidate the key immunological factors responsible for establishing an enhancing, proviral immune environment in place of a protective, antiviral one, thus enabling the identification of novel biomarkers of protection and risk 3) calibrate our mathematical model of innate and adaptive responses to contrast the mechanisms initiating and sustaining adaptive immune responses during primary infection with the immune pathways that are pre-existing and recalled/reactivated during secondary and subsequent infections. These supplies are required for ongoing experiments and are required for use in supporting he ongoing research and clinical trials taking place in the Viral Epidemiology and Immunity Unit (VEIU) of the Laboratory of Infectious Disease (LID). Requirement is for: HU MAGNETIC 30-PLEX KIT 100 TESTS, total 5 each from the SAME LOT, item # LHC6003M, Qty 5
Waiver Rationale Summary
Based on the market research information above, the sources sought results, and the continuity protocols for clinical trials, and market research findings, the feasibility of foregoing the requirement or providing a United States- manufactured substitute has been considered, and no substitutes were found. Authority is requested to acquire the above-described Cytokine 30-Plex Human Panels, manufactured in Austria by Life Technologies for the total cost of $21,238.00. Once the approved waiver is granted, this requirement will be published on the Government Point of Entry (SAM.gov) as a Request for Quotation (RFQ), with a brand name restriction, for a period of fifteen (15) days to provide opportunity to distributors in the marketplace.
Yes
Yes
Consistent with Policy
DRUGS AND BIOLOGICALS
325414 - Biological Product (except Diagnostic) Manufacturing
08/07/2024
N/A
Pre-solicitation
0 - 6 months
Individual Waiver
NATIONAL INSTITUTES OF HEALTH